2025-04-05

A groundbreaking study by a German research team has opened up new possibilities for individuals battling autoimmune diseases.

Wellness
A groundbreaking study by a German research team has opened up new possibilities for individuals battling autoimmune diseases.
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Initial research suggests that CAR-T therapy could be an effective approach for treating and possibly curing certain illnesses.

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Janina Paech, a medical student and lupus patient treated with CAR-T therapy, is photographed in a park near her clinic. Photo by Ksenia Kuleshova for STAT.

ERLANGEN, Germany — In 2021, German researchers announced a significant achievement. They had induced remission in a young woman with severe lupus, a condition causing her organs to fail, using a novel treatment.

Like other autoimmune disorders where the immune system mistakenly attacks the body, lupus is a chronic condition that doesn't simply disappear. For patients, the most hopeful strategy is to manage symptoms with ongoing medication. However, this 20-year-old experienced a remarkable recovery; her disease seemed to vanish completely, allowing her to stop other treatments. 

This was just a single case report, and the team was not widely recognized in the global lupus research community. The paper did not receive much attention. 

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